Increase and uncoupling of adrenomedullin from the natriuretic peptide system in aneurysmal subarachnoid hemorrhage.


OBJECT Natriuresis is a common systemic manifestation of aneurysmal subarachnoid hemorrhage (SAH). Natriuresis and its accompanying hypovolemia may be a major contributing factor in the pathophysiology of symptomatic cerebral vasospasm. METHODS The authors studied 14 consecutive patients with aneurysmal SAH and compared levels of adrenomedullin (ADM), a… (More)


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