Incorporation of the biomarker concept in ecotoxicology calls for a redefinition of terms

@article{Gestel1996IncorporationOT,
  title={Incorporation of the biomarker concept in ecotoxicology calls for a redefinition of terms},
  author={C. V. Gestel and T. C. Brummelen},
  journal={Ecotoxicology},
  year={1996},
  volume={5},
  pages={217-225}
}
Biomarkers have received a lot of attention but the biomarker concept has not yet been defined properly. As a consequence, various interpretations of the term ‘biomarker’ exist, some of which overlap with well-established ecotoxicological concepts. To allow incorporation of the biomarker concept within the framework of modern ecotoxicology, a clarification of terms is needed. In this paper, definitions are presented for the terms ‘biomarker’, ‘bioindicator’ and ‘ecological indicator’, which do… Expand
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References

SHOWING 1-10 OF 26 REFERENCES
The role of biomarkers in environmental assessment (2). Invertebrates
TLDR
It is proposed that, in addition to biomarker measurements on samples obtained from organisms at field sites, biomarker screening tests should be initiated in the laboratory with a range of new chemicals and organisms relevant to the field sites thought to be at risk to establish links between laboratory-based testing and adverse effects in situ. Expand
A critique of the use of distribution-based extrapolation models in ecotoxicology
TLDR
The features and assumptions of recently developed distribution-based extrapolation models that are currently in use (OECD 1991; Van Leeuwen et al. 1992) are examined and it is suggested that the rational use of these models as ecotoxicological tools for environmental regulation requires additional basic knowledge in two areas. Expand
The role of biomarkers in environmental assessment (4). Terrestrial plants
TLDR
It is argued that a battery of biomarkers is necessary to evaluate chemical hazards to species and the efficiency of a biomarker will depend on the degree of already present adaptation to environmental stress and on the homogeneity of the investigated population. Expand
The role of biomarkers in environmental assessment (5). Invertebrate populations and communities
TLDR
Among the various biochemical parameters used as biomarkers in invertebrates exposed to pollutants in the field, only those for which changes at population or community level can be suggested are discussed in the present review. Expand
The role of biomarkers in environmental assessment (3). Vertebrates
TLDR
Suites of biomarkers have the potential to play an important role in environmental assessment and can give information on the effect of pollutants rather than mere quantification of the levels present. Expand
Ecological approaches in soil ecotoxicology
In 1977 the Organization for Economic Co-operation and Development (OECD) established its chemicals testing programme. One of the aims was to prepare state-of-the-art reports on test methods andExpand
Biomarkers : research and application in the assessment of environmental health
Biological markers used to assess the effects of environmental pollution have attracted considerable attention from regulatory agencies and are currently under evaluation at a number of researchExpand
The role of biomarkers in environmental assessment (1). Introduction
TLDR
A series of four papers, commissioned by the European Science Foundation, are presented on the state-of-the-art of the use of biomarkers in environmental assessment and cover invertebrates, vertebrates, plants and invertebrate populations and communities. Expand
The Myth of the Most Sensitive SpeciesMultispecies testing can provide valuable evidence for protecting the environment
TLDR
Although single species toxicity tests form the backbone of the environmental safety testing, it is argued that multispecies testing can provide valuable additional evidence for protecting the environment. Expand
Extrapolation methods for setting ecological standards for water quality: statistical and ecological concerns
TLDR
Extrapolation methods form the basis for most recent techniques used to set ‘safe’ levels of toxicants for ecosystems, but they have not been validated for safety and, before the approach is fully applied, needs to be validated. Expand
...
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