Incorporation of splice site probability models for non-canonical introns improves gene structure prediction in plants

Abstract

MOTIVATION The vast majority of introns in protein-coding genes of higher eukaryotes have a GT dinucleotide at their 5'-terminus and an AG dinucleotide at their 3' end. About 1-2% of introns are non-canonical, with the most abundant subtype of non-canonical introns being characterized by GC and AG dinucleotides at their 5'- and 3'-termini, respectively… (More)
DOI: 10.1093/bioinformatics/bti1205

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