Incorporation of retinoic acid into proteins via retinoyl-CoA.

@article{Renstrom1989IncorporationOR,
  title={Incorporation of retinoic acid into proteins via retinoyl-CoA.},
  author={Britta Renstrom and Hector F DeLuca},
  journal={Biochimica et biophysica acta},
  year={1989},
  volume={998 1},
  pages={69-74}
}
The incorporation of tritiated retinoic acid into proteins has been studied in cell-free extracts from rat liver and kidney. Incubation with retinoic acid in the presence of ATP and CoA resulted in a CoA intermediate. This CoA intermediate is a substrate for enzymes that incorporate the labeled retinoic acid moiety into proteins (Mr = 14,000-60,000) as detected with SDS-polyacrylamide gel electrophoresis. In the microsomal fraction, the label was found in a single protein (Mr 30,000). Retinoic… CONTINUE READING

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