Incorporation of chemoselective functionalities into peptoids via solid-phase submonomer synthesis.

Abstract

A simple route to the introduction of a number of chemoselective functional groups into peptoids (oligo(N-substituted glycines)) by an extension of the standard solid-phase submonomer method is reported. The following groups were introduced: aminooxyacetamide, N-(carbamoylmethyl)acetohydrazide, mercaptoacetamide, 2-pyridinesulfenylmercaptoacetamide, and… (More)

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@article{Horn2004IncorporationOC, title={Incorporation of chemoselective functionalities into peptoids via solid-phase submonomer synthesis.}, author={Thomas Horn and Byoung-Chul Lee and Ken A. Dill and Ronald N. Zuckermann}, journal={Bioconjugate chemistry}, year={2004}, volume={15 2}, pages={428-35} }