Incorporation of alpha-tocopherol in dimyristoylphosphatidylcholine liposomes improves the survival of fibroblasts in culture.

@article{Berrocal1998IncorporationOA,
  title={Incorporation of alpha-tocopherol in dimyristoylphosphatidylcholine liposomes improves the survival of fibroblasts in culture.},
  author={M. C. Berrocal and J. Buj{\'a}n and A. Abeger},
  journal={Drug delivery},
  year={1998},
  volume={5 1},
  pages={
          19-24
        }
}
  • M. C. Berrocal, J. Buján, A. Abeger
  • Published 1998
  • Chemistry, Medicine
  • Drug delivery
  • The use of liposomes as carriers for certain drugs minimizes the adverse effects of high drug concentrations. However, the liposomes themselves may exert toxic effects on human cells, depending on their composition and concentration. The aim of the present investigation was to compare the effects of dimyristoylphosphatidylcholine (DM-PC) liposomes with those of DM-PC liposomes containing alpha-tocopherol on human fibroblasts in culture. DM-PC liposomes had a dose-dependent effect on the growth… CONTINUE READING
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