Incorporation of 14C-tryptophan into 14C-protein by cultured rat pineals: stimulation by l-norepinephrine.

@article{Wurtman1969IncorporationO1,
  title={Incorporation of 14C-tryptophan into 14C-protein by cultured rat pineals: stimulation by l-norepinephrine.},
  author={Richard J. Wurtman and H. M. Shein and Julius Axelrod and F Laren},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1969},
  volume={62 3},
  pages={749-55}
}
Organ cultures of individual rat pineals incorporate (14)C-tryptophan into proteins at a nearly constant rate for at least 48 hours. Previous studies have shown that these cultures also convert (14)C-tryptophan to serotonin, melatonin, and 5-hydroxyindoleacetic acid, and release these indoles into the media. The formation of (14)C-protein from (14)C… CONTINUE READING