Incorporating pathologists' criteria of malignancy into the evolutionary model for cancer development.

@article{Fischer2004IncorporatingPC,
  title={Incorporating pathologists' criteria of malignancy into the evolutionary model for cancer development.},
  author={Andrew H. Fischer and Kyle A. Young and Ronald A DeLellis},
  journal={Journal of cellular biochemistry},
  year={2004},
  volume={93 1},
  pages={28-36}
}
A wide variety of alterations in cell and tissue structure still form the basis for cancer diagnosis by pathologists. Cancer development is recognized to be an evolutionary process [Foulds, 1954; Cairns, 1975; Nowell, 1976; Sager, 1982; Tomlinson et al., 1996; Cahill et al., 1999; Tomlinson and Bodmer, 1999], but the phenotypic changes diagnostic of cancer… CONTINUE READING