Inconsistency in circulating irisin levels: what is really happening?

  title={Inconsistency in circulating irisin levels: what is really happening?},
  author={Fabian Sanchis-Gomar and Rafael Alis and Helios Pareja-Galeano and Marco Romagnoli and Carme P{\'e}rez-Quilis},
  journal={Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme},
  volume={46 8},
The discovery of irisin as a novel and promising peptidic hormone for the treatment of obesity and diabetes has recently been reported. As a result, great hopes have been raised based on this finding, hypothesizing that irisin might provide additional benefits, not only for obesity and diabetes, but also for a wide range of pathological conditions requiring therapeutical and clinical attention. However, controversial results and conclusions on circulating irisin concentrations and correlations… CONTINUE READING