Incomplete and delayed bioavailability of sublingual nitroglycerin.


Eight healthy male volunteers received 16 doses of sublingual nitroglycerin tablets (0.4 mg). After 8 minutes, each subject rinsed out his mouth to halt the drug absorption process. The mouth rinses were assayed by high-performance liquid chromatography for residual nitroglycerin content. Each subject also received intravenous infusions of nitroglycerin so… (More)


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@article{Noonan1985IncompleteAD, title={Incomplete and delayed bioavailability of sublingual nitroglycerin.}, author={Patrick K. Noonan and Leslie Z Benet}, journal={The American journal of cardiology}, year={1985}, volume={55 1}, pages={184-7} }