Inclusion of poorly soluble drugs in highly ordered mesoporous silica nanoparticles.

@article{Thomas2010InclusionOP,
  title={Inclusion of poorly soluble drugs in highly ordered mesoporous silica nanoparticles.},
  author={Mansel J. Thomas and Ian J. Slipper and Akash K. Walunj and Anubhav Jain and Marco Emanuele Favretto and Paraskevi Kallinteri and Dennis Douroumis},
  journal={International journal of pharmaceutics},
  year={2010},
  volume={387 1-2},
  pages={272-7}
}
Silica nanoparticles (MSNs) with a highly ordered mesoporous structures (103A) with cubic Im3 m have been synthesized using triblock copolymers with high poly(alkylene oxide) (EO) segments in acid media. The produced nanoparticles displayed large specific surface area (approximately 765 cm(2)/g) with an average particles size of 120 nm. The loading… CONTINUE READING