Inclusion of 5-[4-(1-dodecanoylpyridinium)]-10,15,20-triphenylporphine in supramolecular aggregates of cationic amphiphilic cyclodextrins: physicochemical characterization of the complexes and strengthening of the antimicrobial photosensitizing activity.

@article{Ferro2009InclusionO5,
  title={Inclusion of 5-[4-(1-dodecanoylpyridinium)]-10,15,20-triphenylporphine in supramolecular aggregates of cationic amphiphilic cyclodextrins: physicochemical characterization of the complexes and strengthening of the antimicrobial photosensitizing activity.},
  author={Stefania Ferro and Giulio Jori and Salvatore Sortino and Rosanna Stancanelli and Peter Nikolov and Giuseppe Tognon and Fernanda Ricchelli and Antonino Mazzaglia},
  journal={Biomacromolecules},
  year={2009},
  volume={10 9},
  pages={2592-600}
}
Recent findings suggest that visible light-promoted photooxidative processes mediated by sensitizers of appropriate chemical structure could represent a useful tool for properly addressing the problem of the increasing occurrence of infectious diseases caused by multiantibiotic-resistant microbial pathogens. The monocationic meso-substituted porphyrin 5-[4-(1-dodecanoylpyridinium)]-10,15,20-triphenyl-porphine (TDPyP) complexed into supramolecular aggregates of cationic amphiphilic beta… CONTINUE READING

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The monocationic meso - substituted porphyrin 5-[4-(1-dodecanoylpyridinium)]-10,15,20-triphenyl - porphine ( TDPyP ) complexed into supramolecular aggregates of cationic amphiphilic beta - cyclodextrin ( SC(6)NH(2 ) ) ( mean diameter = 20 nm ) appeared to be endowed with favorable properties to act as a photosensitizing agent , including a very high quantum yield ( Phi(Delta ) = 0.90 ) for the generation of the highly reactive oxygen species , singlet oxygen ( ( 1)O(2 ) ) .
The monocationic meso - substituted porphyrin 5-[4-(1-dodecanoylpyridinium)]-10,15,20-triphenyl - porphine ( TDPyP ) complexed into supramolecular aggregates of cationic amphiphilic beta - cyclodextrin ( SC(6)NH(2 ) ) ( mean diameter = 20 nm ) appeared to be endowed with favorable properties to act as a photosensitizing agent , including a very high quantum yield ( Phi(Delta ) = 0.90 ) for the generation of the highly reactive oxygen species , singlet oxygen ( ( 1)O(2 ) ) .
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