Inclusion body myositis: current pathogenetic concepts and diagnostic and therapeutic approaches.

@article{Needham2007InclusionBM,
  title={Inclusion body myositis: current pathogenetic concepts and diagnostic and therapeutic approaches.},
  author={Merrilee Needham and Francis L Mastaglia},
  journal={The Lancet. Neurology},
  year={2007},
  volume={6 7},
  pages={620-31}
}
Inclusion body myositis is the most common acquired muscle disease in older individuals, and its prevalence varies among countries and ethnic groups. The aetiology and pathogenesis of sporadic inclusion body myositis are still poorly understood; however genetic factors, ageing, and environmental triggers might all have a role. Unlike other inflammatory myopathies, sporadic inclusion body myositis causes slowly progressing muscular weakness and atrophy, it has a distinctive pattern of muscle… CONTINUE READING

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