Inclusion Complex of Novel Curcumin Analogue CDF and β-Cyclodextrin (1:2) and Its Enhanced In Vivo Anticancer Activity Against Pancreatic Cancer

@article{Dandawate2012InclusionCO,
  title={Inclusion Complex of Novel Curcumin Analogue CDF and β-Cyclodextrin (1:2) and Its Enhanced In Vivo Anticancer Activity Against Pancreatic Cancer},
  author={Prasad R. Dandawate and Alok C Vyas and Aamir Ahmad and S Preeya Banerjee and Jyoti A Deshpande and K. Venkateswara Swamy and Abeda Jamadar and Anne Catherine Dumhe-Klaire and Subhash Padhye and Fazlul H. Sarkar},
  journal={Pharmaceutical Research},
  year={2012},
  volume={29},
  pages={1775-1786}
}
Several formulations have been proposed to improve the systemic delivery of novel cancer therapeutic compounds, including cyclodextrin derivatives. We aimed to synthesize and characterize of CDF-β-cyclodextrin inclusion complex (1:2) (CDFCD). The compound was characterized by Fourier transform infrared, differential scanning calorimetry, powder X-ray diffraction studies, H1 & C13 NMR studies and scanning electron microscopic analysis. Its activity was tested against multiple cancer cell lines… CONTINUE READING
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Correlation of the formation constant of ferrocene-cyclodextrin complexes with dielectric properties of the aqueous DMSO solution

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