Including RNA secondary structures improves accuracy and robustness in reconstruction of phylogenetic trees

@inproceedings{Keller2009IncludingRS,
  title={Including RNA secondary structures improves accuracy and robustness in reconstruction of phylogenetic trees},
  author={Alexander Keller and Frank F{\"o}rster and Tobias Mueller and Thomas Dandekar and Joerg Schultz and Matthias Wolf},
  booktitle={Biology Direct},
  year={2009}
}
In several studies, secondary structures of ribosomal genes have been used to improve the quality of phylogenetic reconstructions. An extensive evaluation of the benefits of secondary structure, however, is lacking. This is the first study to counter this deficiency. We inspected the accuracy and robustness of phylogenetics with individual secondary structures by simulation experiments for artificial tree topologies with up to 18 taxa and for divergency levels in the range of typical… CONTINUE READING

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