Incidental detection of gastrointestinal stromal tumor by Tc-99m MDP bone scan.


This case demonstrates extraosseous 99m-technetium methylene diphosphonate (Tc-99m MDP) accumulation from a gastrointestinal stromal tumor. A 75-year-old woman underwent a temporal bone CT for conductive hearing loss that showed sclerosis in the right occipital condyle. Follow-up Tc-99m MDP bone scan for osseous metastases instead showed a mass-like extraosseous accumulation of Tc-99m MDP in the anterior left upper quadrant. Differential diagnoses included gastric cancer, lymphoma, metastatic melanoma, systemic hypercalcemia, or heterotopic mesenteric ossification. Contrast CT showed a well-circumscribed mass arising from the stomach, and subsequent pathology confirmed gastrointestinal stromal tumor. These tumors rarely can contain osteoclast-like giant cells and should be considered for extraosseous Tc-99m MDP accumulation.

DOI: 10.1097/RLU.0b013e31823e9f95


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@article{Shepherd2012IncidentalDO, title={Incidental detection of gastrointestinal stromal tumor by Tc-99m MDP bone scan.}, author={Timothy M. Shepherd and Ibrahim A Idakoji and Miguel Hernandez Pampaloni}, journal={Clinical nuclear medicine}, year={2012}, volume={37 2}, pages={198-9} }