Incidence of the JAK2 V617F mutation among patients with splanchnic or cerebral venous thrombosis and without overt chronic myeloproliferative disorders.

@article{Stefano2007IncidenceOT,
  title={Incidence of the JAK2 V617F mutation among patients with splanchnic or cerebral venous thrombosis and without overt chronic myeloproliferative disorders.},
  author={Valerio De Stefano and Ada Fiorini and Edoardo Rossi and Tommaso Za and Giampaolo Farina and Patrizia Chiusolo and Simona Sica and Gilda Leone},
  journal={Journal of thrombosis and haemostasis : JTH},
  year={2007},
  volume={5 4},
  pages={708-14}
}
BACKGROUND Thrombosis of splanchnic or cerebral veins is a typical manifestation of polycythemia vera (PV) or essential thrombocythemia (ET). The recently identified Janus kinase 2 (JAK2) V617F somatic mutation is closely related to chronic myeloproliferative disorders (CMD). OBJECTIVE To assess the incidence of the JAK2 V617F mutation among patients with splanchnic or cerebral venous thrombosis with or without overt CMD. PATIENTS AND METHODS We searched for the mutation in 139 adult… CONTINUE READING

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