Incidence of skeletal complications during treatment of childhood acute lymphoblastic leukemia: comparison of fracture risk with the General Practice Research Database.

@article{Hgler2007IncidenceOS,
  title={Incidence of skeletal complications during treatment of childhood acute lymphoblastic leukemia: comparison of fracture risk with the General Practice Research Database.},
  author={Wolfgang H{\"o}gler and Goetz Wehl and Tjeerd P van Staa and Bernhard Meister and Andreas Klein-Franke and Gabriele Kropshofer},
  journal={Pediatric blood & cancer},
  year={2007},
  volume={48 1},
  pages={21-7}
}
BACKGROUND Skeletal complications during or after treatment of acute lymphoblastic leukemia (ALL) have been frequently reported and can cause substantial morbidity, yet their incidence is not well established. The present study assessed the incidence of fractures, osteonecrosis (ON), and bone pain during ALL treatment and compared the fracture incidence with age- and sex-specific reference data from the UK General Practice Research Database (GPRD). PROCEDURE Medical records of 122 ALL… CONTINUE READING

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