Incidence of sexually transmitted infections before and after preexposure prophylaxis for HIV

@article{Nguyen2017IncidenceOS,
  title={Incidence of sexually transmitted infections before and after preexposure prophylaxis for HIV},
  author={Vinh-Kim Nguyen and Zo{\"e} R. Greenwald and Helen Trottier and Martha Cadieux and Alexandre Goyette and Mari{\`e}ve Beauchemin and Louise Charest and Dani{\`e}le Longpr{\'e} and St{\'e}phane Lavoie and Hermione Gbego Tossa and R{\'e}jean Thomas},
  journal={AIDS (London, England)},
  year={2017},
  volume={32},
  pages={523 - 530}
}
Objective: Use of preexposure prophylaxis (PrEP) for HIV raises concerns about sexually transmitted infection (STI) incidence because of decreased condom use among MSM. This study examines whether PrEP is associated with STIs in the 12 months following PrEP prescription relative to the 12 months prior to PrEP and if STI rates are higher among PrEP users relative to individuals receiving postexposure prophylaxis (PEP). Design: Retrospective cohort study including PrEP users with more than 12… 
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99 Citations
Highly Influential Citations
6
Background Citations
30
Methods Citations
1
Results Citations
7

99 Citations

Incidence and risk factors for recurrent sexually transmitted infections among MSM on HIV pre-exposure prophylaxis

STI incidence was high and increased over time and most STIs were concentrated in a high-risk group that should be targeted for future interventions.

Sexually Transmitted Infection Testing and Prevalence Before and After Preexposure Prophylaxis Initiation Among Men Aged ≥18 Years in US Private Settings

High STI prevalence before and after PrEP initiation in this study suggests that patients taking PrEP have an increased risk of acquiring STI.

Association of HIV Preexposure Prophylaxis With Incidence of Sexually Transmitted Infections Among Individuals at High Risk of HIV Infection

Among gay and bisexual men using PrEP, STIs were highly concentrated among a subset, and receipt of PrEP after study enrollment was associated with an increased incidence of STIs compared with preenrollment, highlighting the importance of frequent STI testing.

Concerns about a study on sexually transmitted infections after initiation of HIV preexposure prophylaxis.

Concerns are raised about this study, particularly with respect to study design and the degree to which the results support the conclusions of Nguyen et al.

HIV Pre-Exposure Prophylaxis and Increased Incidence of Sexually Transmitted Infections in the United States.

The implementation and utilization of HIV PrEP in the U.S. were associated with increased rates of STIs and further studies to confirm this association and to elucidate potential causes are needed.

Chemsex and incidence of sexually transmitted infections among Canadian pre-exposure prophylaxis (PrEP) users in the l’Actuel PrEP Cohort (2013–2020)

The high STI incidence among gbMSM who report chemsex highlights the importance of PrEP for this population and the need for integrated services that address the complexities of sexualised substance use.

HIV pre-exposure prophylaxis and sexually transmitted infections: intersection and opportunity

The successes and challenges of pre-exposure prophylaxis to date, its place as part of robust strategies to reduce HIV infections, the rising rates of curable sexually transmitted diseases and their relationship with HIV prevention, and future directions for synergies in PrEP and sexually transmitted disease prevention are discussed.

Sexually transmitted infections among participants in an HIV PrEP adherence trial

It was found that the incidence of STIs was not significantly different between those adherent to PrEP and those non-adherent, and further research is needed to assess how PrEP use may impact STIs over time.

Assessment for sexually transmitted infections in men who have sex with men attending a nurse-run HIV preexposure prophylaxis clinic

  • J. Stockton
  • Medicine
    Journal of the American Association of Nurse Practitioners
  • 2021
Sexually transmitted infection results in this population are consistent with those reported in other PrEP centers and reinforce importance of three-point chlamydia/gonorrhea testing as part of comprehensive STI evaluation.

Low use of condom and high STI incidence among men who have sex with men in PrEP programs

The incidence of STI acquisition was higher than expected, indicating a need for strategies to minimize this impact, particularly among younger individuals with a higher number of sexual partners.
...

References

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