Incidence of severe combined immunodeficiency through newborn screening in a Chinese population.

@article{Chien2015IncidenceOS,
  title={Incidence of severe combined immunodeficiency through newborn screening in a Chinese population.},
  author={Yin-Hsiu Chien and S H Chiang and Kai-Ling Chang and H I Yu and W Lee and Li-Ping Tsai and Li-Wen Hsu and Min-Huei Hu and W L Hwu},
  journal={Journal of the Formosan Medical Association = Taiwan yi zhi},
  year={2015},
  volume={114 1},
  pages={12-6}
}
BACKGROUND/PURPOSE In order to know the true incidence of severe combined immunodeficiency (SCID) in a Chinese population, we conducted and implemented SCID newborn screening in Taiwan. METHODS Between May 1, 2010 and December 31, 2011, the National Taiwan University Hospital Newborn Screening Center screened all newborns for T-cell lymphopenia by measuring the copy number of T-cell receptor excision circles (TRECs) and RNase P. Newborns with low TREC values were subjected to complete blood… CONTINUE READING
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