Incidence of new primary cancers after adjuvant tamoxifen therapy and radiotherapy for early breast cancer.

@article{Andersson1991IncidenceON,
  title={Incidence of new primary cancers after adjuvant tamoxifen therapy and radiotherapy for early breast cancer.},
  author={Michael Andersson and Hans Henrik Storm and Henning T. Mouridsen},
  journal={Journal of the National Cancer Institute},
  year={1991},
  volume={83 14},
  pages={
          1013-7
        }
}
The incidence of new primary cancers was evaluated in 3538 postmenopausal patients who had received surgical treatment for primary breast cancer. Of these patients, 1828 with a low risk of recurrence received no further treatment. High-risk patients were randomly assigned to one of two groups. The first group (n = 846) received postoperative radiotherapy, while the second group (n = 864) received radiotherapy plus tamoxifen at a dose of 30 mg given daily for 48 weeks. The median observation… CONTINUE READING

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