Incidence of nephrotoxicity and association with vancomycin use in intensive care unit patients with pneumonia: retrospective analysis of the IMPACT-HAP Database.

@article{Cano2012IncidenceON,
  title={Incidence of nephrotoxicity and association with vancomycin use in intensive care unit patients with pneumonia: retrospective analysis of the IMPACT-HAP Database.},
  author={Ennie L Cano and Nadia Z Haque and Verna L Welch and Cynthia M. Cely and Paula Peyrani and Ernesto G. Scerpella and Kimbal D. Ford and Marcus John Zervos and Julio A. Ramirez and Daniel H. Kett},
  journal={Clinical therapeutics},
  year={2012},
  volume={34 1},
  pages={149-57}
}
BACKGROUND The 2005 guidelines from the American Thoracic Society and the Infectious Diseases Society of America recommend vancomycin trough levels of 15 to 20 mg/L for the therapy of hospital-acquired (HAP), ventilator-associated (VAP), and health care-associated (HCAP) pneumonia. OBJECTIVE The goal of this article was to report the incidence of nephrotoxicity and associated risk factors in intensive care unit patients who received vancomycin for the treatment of HAP, VAP, and HCAP… CONTINUE READING

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