Incidence of failure of immune passive transfer (FPT) in thoroughbred foals - Interest of a rapid diagnosis for FPT

Abstract

Although newborn foals are immuno-competent, they are immunologically naive because of the failure of immunoglobulin transfer through the placenta [6, 7, 9]. Immunoglobulin production begins when foals were exposed to antigens. But adequate concentrations of immunoglobulins can be only reached up to two months of age [6]. Consequently, infectious diseases are major cause of death in neonatal foals, and the passive transfer of maternal antibodies via colostrum constitutes the most effective defense for newborn foals against pathogens until their own immune systems completely developed [5]. Colostrum absorption is maximal during the first six hours after birth, and then decreases gradually until 24 hours [3]. FPT may be a contributory cause of serious neonatal infection and septicemia in foals for the first two months of life [9, 10].

1 Figure or Table

Cite this paper

@inproceedings{KALINBACAK2005IncidenceOF, title={Incidence of failure of immune passive transfer (FPT) in thoroughbred foals - Interest of a rapid diagnosis for FPT}, author={A . KALINBACAK and Murat Guzel and Inci Altintas}, year={2005} }