Incidence of esophageal adenocarcinoma in Barrett's esophagus with low-grade dysplasia: a systematic review and meta-analysis.

@article{Singh2014IncidenceOE,
  title={Incidence of esophageal adenocarcinoma in Barrett's esophagus with low-grade dysplasia: a systematic review and meta-analysis.},
  author={Siddharth Singh and Palaniappan Manickam and Anita V Amin and Niharika Samala and Leo J Schouten and Prasad G Iyer and Tusar K. Desai},
  journal={Gastrointestinal endoscopy},
  year={2014},
  volume={79 6},
  pages={
          897-909.e4; quiz 983.e1, 983.e3
        }
}
BACKGROUND The natural history of low-grade dysplasia (LGD) in patients with Barrett's esophagus (BE) is unclear. OBJECTIVE We performed a systematic review and meta-analysis of studies that reported the incidence of esophageal adenocarcinoma (EAC) and/or high-grade dysplasia (HGD) among patients with BE with LGD. DESIGN Systematic review and meta-analysis of cohort studies. PATIENTS Patients with BE-LGD, with mean cohort follow-up ≥ 2 years. MAIN OUTCOME MEASUREMENTS Pooled incidence… CONTINUE READING

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