Incidence of anticonvulsant osteomalacia and effect of vitamin D: controlled therapeutic trial.

@article{Christiansen1973IncidenceOA,
  title={Incidence of anticonvulsant osteomalacia and effect of vitamin D: controlled therapeutic trial.},
  author={Claus Christiansen and P Rodbro and Michael Shane Lund},
  journal={British medical journal},
  year={1973},
  volume={4 5894},
  pages={
          695-701
        }
}
The bone mineral content (B.M.C.) in both forearms (related to total body calcium) was measured by photon absorptiometry for a controlled therapeutic trial in a representative sample of epileptic outpatients, comprising 226 patients treated with one or two major anticonvulsant drugs (phenytoin, phenobarbitone, primidone).Initially the mean B.M.C. value for all epileptic patients was 87% of normal. During treatment with 2,000 international units of vitamin D(2) daily for three months an average… CONTINUE READING

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