Corpus ID: 78768587

Incidence of Endoscopic Findings and Related Risk Factors in Patients with Gastrointestinal Bleeding after Percutaneous Coronary Intervention and Combination Antiplatelet Therapy

  title={Incidence of Endoscopic Findings and Related Risk Factors in Patients with Gastrointestinal Bleeding after Percutaneous Coronary Intervention and Combination Antiplatelet Therapy},
  author={Neda Nozari},
Background: Combination antiplatelet therapy is a classic treatment for percutaneous coronary intervention (PCI) but this therapy increases gastrointestinal bleeding (GIB). This study highlights the incidence of related risk factors of GIB and endoscopic findings in patients with GIB after PCI and combination antiplatelet therapy. Materials and Methods: A standard check list was used to evaluate the significant risk factors of GIB and upper endoscopic findings in combination antiplatelet… Expand


Clinical Risk Factors for Upper Gastrointestinal Bleeding after Percutaneous Coronary Intervention: A Single-Center Study
Clinicians must remain vigilant for the possibility of UGIB after PCI and should consider performing timely endoscopy in patients who have undergone PCI and are suspected of having an UG IB. Expand
High prevalence of ulcer bleeding risk factors in dual antiplatelet-treated patients after percutaneous coronary intervention.
This study demonstrates a high prevalence of risk factors among PCI patients treated with dual antiplatelet therapy, many of whom were not in PPI treatment. Expand
Clinical Impact of Gastrointestinal Bleeding in Patients Undergoing Percutaneous Coronary Interventions
Triple antithrombotic therapy emerged as the single drug-related predictor of GIB in addition to patient-related risk factors within 1 year of PCI, and was an independent predictor of all-cause mortality during 1 year. Expand
[Gastrointestinal bleeding in patients undergoing primary angioplasty for acute myocardial infarction: incidence, risk factors and prognosis].
Increased inotropic requirement, age above 70 years, and impaired renal function are independent predictors of this complication in patients undergoing primary PCI for ST-elevation myocardial infarction. Expand
Lower GI bleeding is more common than upper among patients on dual antiplatelet therapy: long-term follow-up of a cohort of patients commonly using PPI co-therapy
Among patients on dual antiplatelet therapy and PPI co-therapy, gastrointestinal bleeding episodes are more frequent in the lower GI tract, which may reflect the success of gastroprotection and focuses attention on research to address lower GI bleeding in this population. Expand
Gastrointestinal Bleeding after Percutaneous Coronary Intervention
There are few randomized controlled trials assessing the best strategy for the prevention of GI bleeding after PCI and further extensive studies are required to ascertain the beneficial effect of prophylactic agents for dual antiplatelet therapy following PCI. Expand
Gastrointestinal bleeding in patients with acute coronary syndromes: incidence, predictors, and clinical implications: analysis from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial.
GIB is a serious condition in the scenario of ACS and is independently associated with mortality and ischemic complications, and older age, baseline anemia, longer duration of study drug administration before angiogram, smoking, ST-segment deviation>, and diabetes were identified as independent predictors of GIB. Expand
Incidence of Gastrointestinal Bleeding After Percutaneous Coronary Intervention: A Single Center Experience
  • F. Aziz
  • Medicine
  • Cardiology research
  • 2014
Although, GI bleeding in patients with MI significantly increases mortality and morbidity, previous GI bleeding and higher Killip class are associated with higher incidence of GI bleeding. Expand
Overt gastrointestinal bleeding in patients with acute myocardial infarction: retrospective analysis of risks and outcomes
In patients with AMI, overt GIB is associated with higher in-hospital mortality, and female sex, older age, prior AmI, pneumonia and anemia at admission are predictors of Overt GIB during hospitalization. Expand
Proton-pump inhibitors can decrease gastrointestinal bleeding after percutaneous coronary intervention.
Advanced age, being female, smokers, drinkers, previous peptic ulcer and previous gastrointestinal bleeding were significant independent risk factors for gastrointestinal bleeding, and proton-pump inhibitor use after PCI was safe and effective. Expand