Incidence of Class 1 Integrons in a Quaternary Ammonium Compound-Polluted Environment

@article{Gaze2005IncidenceOC,
  title={Incidence of Class 1 Integrons in a Quaternary Ammonium Compound-Polluted Environment},
  author={W. Gaze and N. Abdouslam and P. Hawkey and E. Wellington},
  journal={Antimicrobial Agents and Chemotherapy},
  year={2005},
  volume={49},
  pages={1802 - 1807}
}
ABSTRACT Samples of effluent and soil were collected from a reed bed system used to remediate liquid waste from a wool finishing mill with a high use of quaternary ammonium compounds (QACs) and were compared with samples of agricultural soils. Resistance quotients of aerobic gram-negative and gram-positive bacteria to ditallowdimethylammomium chloride (DTDMAC) and cetyltrimethylammonium bromide (CTAB) were established by plating onto nutrient agar containing 5 μg/ml or 50 μg/ml DTDMAC or CTAB… Expand
Waste water effluent contributes to the dissemination of CTX-M-15 in the natural environment
TLDR
The discovery of the first examples of blaCTX-M-15 in UK river sediment proves that evolution of novel combinations of resistance genes is occurring at high frequency and has to date been significantly underestimated. Expand
Impacts of anthropogenic activity on the ecology of class 1 integrons and integron-associated genes in the environment
TLDR
It is shown that prevalence of class 1 integrons is higher in bacteria exposed to detergents and/or antibiotic residues, specifically in sewage sludge and pig slurry compared with agricultural soils to which these waste products are amended. Expand
Class 1 Integrons and the Antiseptic Resistance Gene (qacEΔ1) in Municipal and Swine Slaughterhouse Wastewater Treatment Plants and Wastewater—Associated Methicillin-Resistant Staphylococcus aureus
  • M. Wan, C. Chou
  • Biology, Medicine
  • International journal of environmental research and public health
  • 2015
TLDR
This study provides important evidence regarding the abundances of intI1 and qacEΔ1 genes in municipal and swine slaughterhouse wastewater, and antiseptic-resistant MRSA strains were detected in swine Slaughterhouse wastewater. Expand
Quantification and Characterization of Antimicrobial Resistance in Greywater Discharged to the Environment
TLDR
Results from this study indicate that greywater can be a source of ARB, including ESBL producers, in settings characterized by low sanitary conditions and inadequate wastewater management. Expand
Prevalence and characterization of integrons from bacteria isolated from a slaughterhouse wastewater treatment plant.
TLDR
The hypothesis that WWTPs constitute a potential hot spot for horizontal gene transfer and for selection of antimicrobial resistance genes among aquatic bacteria is supported. Expand
Distribution and Sequencing of Class 1 Integrons Carrying qac Gene Cassettes in Environment Sample
  • X. Duan, W. Gong
  • Biology
  • 2010 4th International Conference on Bioinformatics and Biomedical Engineering
  • 2010
TLDR
From the observations in the present study, it is evident that integrons carrying qac gene cassettes are prevalent among environment samples, showing definite influence on the development of antibiotic resistance. Expand
The widespread dissemination of integrons throughout bacterial communities in a riverine system
TLDR
It is demonstrated through isolation and culture-independent analysis that WWTP effluent significantly increases both CL1 abundance and antibiotic resistance in the riverine environment, and demonstrates the widespread carriage of clinically important resistance determinants by environmentally associated bacteria. Expand
Widespread dissemination of class 1 integron components in soils and related ecosystems as revealed by cultivation-independent analysis
TLDR
In this study, insights are provided into the occurrence of genes typically associated with the class 1 integrons in previously not studied environments with or without human impact and their association with IncP-1 plasmids. Expand
Characterization and transferability of class 1 integrons in commensal bacteria isolated from farm and nonfarm environments.
TLDR
The presence of class 1 integrons among diverse commensal bacteria from agricultural and nonfarm environments strengthens the possible role of environmental commensals in serving as reservoirs of antibiotic resistance genes. Expand
Diverse Gene Cassettes in Class 1 Integrons of Facultative Oligotrophic Bacteria of River Mahananda, West Bengal, India
TLDR
Oligotrophic bacteria are good sources of novel genes as well as potential reservoirs of antibiotic resistance gene casettes, and Antibiotic-sensitive isolates have a greater propensity to carry gene cassettes unrelated to known antibiotic-resistance genes. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 49 REFERENCES
Identification and characterization of class 1 integrons in bacteria from an aquatic environment.
TLDR
This study confirms the occurrence of integrons in bacteria from a natural habitat and suggests that in the absence of continued antibiotic selective pressures, integrons which persist appear to preferentially exist without integrated antibiotic resistance gene cassettes. Expand
Effects of Quaternary-Ammonium-Based Formulations on Bacterial Community Dynamics and Antimicrobial Susceptibility
TLDR
Data demonstrate the recalcitrance of domestic drain biofilms toward QAC and that although repeated QAC exposure of drain isolates in pure culture results in susceptibility change in some test bacteria, such changes do not necessarily occur within complex communities. Expand
Incidence and Characterization of Integrons, Genetic Elements Mediating Multiple-Drug Resistance, in AvianEscherichia coli
TLDR
Characterization of the identified integrons revealed that many were part of the transposon Tn21, a genetic element that encodes both antibiotic resistance and heavy-metal resistance to mercuric compounds, which suggests the mobility of Tn 21 among pathogens in humans as well as poultry. Expand
The qacG gene on plasmid pST94 confers resistance to quaternary ammonium compounds in staphylococci isolated from the food industry
TLDR
The ability of sublethal concentrations of BC to develop cross‐resistance and induce efflux mechanisms could be of practical significance; it should be considered before use of any new disinfectant and in the design of better disinfection procedures. Expand
Class 1 integrons mediate antibiotic resistance in the fish pathogen Aeromonas salmonicida worldwide.
TLDR
The gene cassettes reported in this study are all described in bacteria associated with humans, and this demonstrates once more how the common gene pool is shared between organisms belonging to different environments. Expand
The Staphylococcus qacH gene product: a new member of the SMR family encoding multidrug resistance.
TLDR
F fluorimetry indicated that the high-level ethidium bromide resistance was due to improved efflux energised by the proton motive force, and site-directed mutagenesis substituting the Asp-24 residue with Glu-24 had no effect on resistance characteristics. Expand
Characterization of In40 of Enterobacter aerogenes BM2688, a Class 1 Integron with Two New Gene Cassettes, cmlA2 and qacF
TLDR
Study of the antibiotic-susceptible derivative BM2688-1 indicated that a 3,148-bp deletion between the 3′ end of theaac(6′)-Ib gene and the3′ conserved segment of In40 was responsible for the loss of resistance. Expand
Do Biocides Select for Antibiotic Resistance? *
  • A. D. Russell
  • Medicine, Biology
  • The Journal of pharmacy and pharmacology
  • 2000
TLDR
It remains to be determined how an increase to low‐level resistance to cationic biocides can be held responsible for the selection of antibiotic‐resistant bacteria. Expand
Association of qacE and qacEDelta1 with multiple resistance to antibiotics and antiseptics in clinical isolates of Gram-negative bacteria.
TLDR
The data indicate that multiply antibiotic-resistant Gram-negative bacteria are not necessarily more resistant to quaternary ammonium compounds than antibiotic-sensitive strains even though qacE or qacEDelta1 is present. Expand
Characterization of class 1 integrons associated with R-plasmids in clinical Aeromonas salmonicida isolates from various geographical areas.
TLDR
It appears that integron-encoded antibiotic resistance genes contribute substantially to the horizontal spread of antimicrobial resistance within Aeromonas salmonicida, being associated with conjugative plasmids. Expand
...
1
2
3
4
5
...