Incidence and risk factors for bleeding in 1104 patients with essential thrombocythemia or prefibrotic myelofibrosis diagnosed according to the 2008 WHO criteria

@article{Finazzi2012IncidenceAR,
  title={Incidence and risk factors for bleeding in 1104 patients with essential thrombocythemia or prefibrotic myelofibrosis diagnosed according to the 2008 WHO criteria},
  author={G. Finazzi and A. Carobbio and J. Thiele and F. Passamonti and E. Rumi and M. Ruggeri and F. Rodeghiero and M. Randi and I. Bertozzi and A. Vannucchi and E. Antonioli and H. Gisslinger and V. Buxhofer-Ausch and N. Gangat and A. Rambaldi and A. Tefferi and T. Barbui},
  journal={Leukemia},
  year={2012},
  volume={26},
  pages={716-719}
}
  • G. Finazzi, A. Carobbio, +14 authors T. Barbui
  • Published 2012
  • Medicine
  • Leukemia
  • In an international study of 1104 patients with essential thrombocythemia (ET), a histological review according to the 2008 World Health Organization (WHO) criteria confirmed ET in 891 patients (WHO-ET, 81%), and revised the diagnosis to prefibrotic primary myelofibrosis (PMF) in 180 patients (PMF, 16%). Major bleeding during follow-up occurred in 55 (6%) WHO-ET and 21 (12%) PMF patients (P=0.009), at a rate of 0.79 and 1.39% patients per year, respectively, (P=0.039). In a multivariable… CONTINUE READING

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