Incidence and predictors of screen failures due to positive urine tests for alcohol, drugs of abuse, and cotinine among normal healthy research volunteers (NHRVs): analysis of data from 687 NHRVs screened at a large clinical pharmacology unit in the United States.

Abstract

Accurate medical histories for all NHRVs screening to participate in clinical pharmacology trials are vital to ensure volunteers' safety, and integrity of study results. Evidence from previous studies illustrate the potential for NHRVs to misrepresent their histories, especially when monetary incentives are offered, and the need to objectively verify these… (More)
DOI: 10.1097/MJT.0b013e3181727c12

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@article{Nada2008IncidenceAP, title={Incidence and predictors of screen failures due to positive urine tests for alcohol, drugs of abuse, and cotinine among normal healthy research volunteers (NHRVs): analysis of data from 687 NHRVs screened at a large clinical pharmacology unit in the United States.}, author={Adel Mohamed Nada and Shawn Baxter and Erik K Loraas and John Somberg}, journal={American journal of therapeutics}, year={2008}, volume={15 3}, pages={214-20} }