Incidence and mutation rates of Huntington's disease in Spain: experience of 9 years of direct genetic testing.

@article{RamosArroyo2005IncidenceAM,
  title={Incidence and mutation rates of Huntington's disease in Spain: experience of 9 years of direct genetic testing.},
  author={Mar{\'i}a Antonia Ramos-Arroyo and S. Gonz{\'a}lez Moreno and A. Rodr{\'i}guez Valiente},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={2005},
  volume={76 3},
  pages={337-42}
}
BACKGROUND Prior to the discovery of the Huntington's disease (HD) mutation, the prevalence, incidence, and new mutation rates for this disease were based on the presence of progressive choreic movements and a positive family history. OBJECTIVE To evaluate the uptake of the HD genetic analysis in Spain, and to provide additional information on the epidemiology of this disease from the experience of 9 years of direct genetic testing. METHODS From 1994 to 2002, CAG repeat length was… CONTINUE READING
23 Citations
19 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 23 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 19 references

Molecular analysis of the IT 15 gene in 79 Spanish families with Huntington ’ s disease : diagnostic confirmation and presymptomatic diagnosis

  • SE Andrew, YP Goldberg, B Kremer
  • Med Clin ( Barc )
  • 1997

Molecular analysis of the IT 15 gene in patients with apparently ‘ sporadic ’ Huntington ’ s disease

  • S Siesling, M Vegter-vandeVlis, M Losekoot
  • Eur Neurol
  • 1996

The epidemiology of Huntington ’ s disease

  • PS Harper
  • Huntington ’ s disease
  • 1996

Enfermedad de Huntington en la provincia de Cádiz

  • A Calcedo-Ordoñez
  • Arch Neurol
  • 1994

Similar Papers

Loading similar papers…