Incidence and associations of acute kidney injury after major abdominal surgery

  title={Incidence and associations of acute kidney injury after major abdominal surgery},
  author={M E O'Connor and Christopher J. Kirwan and Rupert M. Pearse and John R. Prowle},
  journal={Intensive Care Medicine},
PurposeAcute kidney injury (AKI) is a recognised risk factor for adverse outcomes in critical illness and hospitalised patients in general. To understand the incidence and associations of AKI as a peri-operative complication of major abdominal surgery, we conducted a systematic literature review and meta-analysis.MethodsUsing a systematic strategy, we searched the electronic reference databases for articles describing post-operative renal outcomes using consensus criteria for AKI diagnosis… 
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The occurrence and severity of AKI are strongly associated with risk of death after surgery, however, the relationship between preoperative renal function as assessed by serum creatinine-based eGFR and risk of died dependent on patient age and whether AKI develops postoperatively.
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Acute kidney injury is common after major trauma and associated with increased mortality and future research is warranted to reduce the potential for harm associated with this subtype of AKI.
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In this cohort of patients submitted to major abdominal surgery, persistent AKI was an independent predictor of in-hospital mortality in contrast to transient AKI.
Postoperative acute kidney injury in high-risk patients undergoing major abdominal surgery.
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    BJS open
  • 2021
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Incidence and Predictors of Acute Kidney Injury in Patients Undergoing Elective Hepatic Resection for Malignant Tumors: A 3-year Prospective Observational Study
AKI after elective hepatic resection occurred in nearly one-third of the authors' patients, and age, BMI, and need for postoperative ventilation were independent predictors of postoperative AKI.


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It is shown that acute kidney injury was common in patients undergoing major abdominal surgery and was associated with in-hospital mortality, and postoperative AKI was related with increased in- hospital mortality.
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Perioperative risk factors for AKI after liver resection surgery are similar to those established for other surgical procedures, and interventions on modifiable risk factors can reduce the incidence of postoperative AKI and improve patient outcome.
Incidence, Predictive Factors, and Clinical Outcomes of Acute Kidney Injury after Gastric Surgery for Gastric Cancer
A retrospective study of patients with normal renal function who underwent partial or total gastrectomy for gastric cancer between June 2002 and December 2011 identified several factors associated with postoperative AKI; recognition of these predictive factors may help reduce the incidence of AKI.
Acute Kidney Injury After Major Surgery: A Retrospective Analysis of Veterans Health Administration Data.
  • M. Grams, Y. Sang, C. Kovesdy
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    American journal of kidney diseases : the official journal of the National Kidney Foundation
  • 2016
AKI was common after major surgery, with similar risk factor and outcome associations across surgery type, and can inform the design of clinical trials in postoperative AKI to the noncardiac surgery setting.
The incidence and risk factors of acute kidney injury after hepatobiliary surgery: a prospective observational study
Urine NGAL was useful in the early diagnosis of postoperative AKI as well as in predicting the 6 months renal outcome after hepatobiliary surgery, and the maximum urine NGAL level during 24 h postsurgery, intraoperative fluid balance, and having liver transplantation were significantly associated with a poor 6  Months renal outcome.
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This study shows that age, emergency and high risk surgery, ischemicHeart disease, congestive heart disease, ASA physical status and RCRI score were considered risk factors for the development of AKI, in patients needing intensive care after surgery.
Risk factors of postoperative acute kidney injury in patients undergoing esophageal cancer surgery.
Postoperative AKI is common in patients undergoing esophageal cancer surgery for cancer and closer evaluation and monitoring in patients with risk factors for AKI may be warranted.
Preoperative statin use and postoperative acute kidney injury.
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