Incidence and Predictors of Reinfection with Trichomonas vaginalis in HIV‐infected Women

  title={Incidence and Predictors of Reinfection with Trichomonas vaginalis in HIV‐infected Women},
  author={L. M. Niccolai and Jeff Kopicko and Ayalnesh Asmamaw Kassie and Hezkiel Petros and Rachel A. Clark and Patricia J Kissinger},
  journal={Sexually Transmitted Diseases},
Background and Objectives: The presence of sexually transmitted infections (STIs) may facilitate transmission of HIV to uninfected partners. Goal: To describe the incidence of reinfection with Trichomonas vaginalis in HIV‐infected women and to assess predictors of reinfection. Study Design: A retrospective cohort study using data abstracted from medical records of HIV‐infected women with at least one diagnosis of trichomoniasis. Results: Approximately one third (36%) of the study population was… 

Incidence and predictors of reinfection with trichomoniasis based on nucleic acid amplification testing results in HIV-infected patients

The incidence and predictors of T. vaginalis reinfection was high among HIV-infected women in this sample, necessitating enhanced disease control efforts in this high-risk population of women in Birmingham, Alabama.

Trichomonas vaginalis infection among women receiving gynaecological care at an Alabama HIV Clinic

T vaginalis remains highly prevalent among HIV-infected women, a proportion of which may be asymptomatic, and increased emphasis on screening for high risk sexual behaviours, testing for T vaginalis, and risk reduction counselling is necessary.

The influence of ART on the treatment of Trichomonas vaginalis among HIV-infected women.

  • A. AdamskiR. Clark P. Kissinger
  • Medicine
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2014
ART usage was associated with a higher TV persistent infection rate among those receiving the single-dose treatment, but not the multidose, providing more evidence that multidosing should be the preferred treatment for HIV+ women.

Early repeated infections with Trichomonas vaginalis among HIV-positive and HIV-negative women.

High rates of treatment failure among both HIV-positive and HIV-negative women indicate that a 2-g dose of metronidazole may not be adequate for treatment of some women and that rescreening should be considered.

Genital Infections of HIV-Infected Women Assisted by a Specialized Service

The most frequent infection was BV with persistence/recurrence of 52.4%, which was associated with a longer time period between treatment and cure control, postmenopausal period, and having a steady partner.

Patient-Delivered Partner Treatment and Trichomonas vaginalis Repeat Infection Among Human Immunodeficiency Virus-Infected Women

HIV-infected women with TV reported high adherence to patient delivered partner treatment (PDPT), and treatment failure was the most common probable cause of repeat infection.

Trichomonas vaginalis infection in human immunodeficiency virus-seropositive Nigerian women: The public health significance

Education efforts must be aimed at sexually active persons and high risk groups and are best focused upon the use of barrier precautions, particularly condom use, according to evidence from the biology and epidemiology of Trichomonas vaginalis.

Trichomonas vaginalis screening and prevention in order to impact the HIV pandemic: Isn't it time we take this infection seriously?

  • G. Lazenby
  • Medicine, Biology
    Infectious disease reports
  • 2011
Treatment of TV has demonstrated lower rates of HIV acquisition in at risk women and initiation of an effective TV screening and treatment program in HIV positive and HIV susceptible populations may limit further transmission of HIV.

Factors associated with the prevalence and incidence of Trichomonas vaginalis infection among African American women in New York city who use drugs.

African American women who used drugs and were screened for Trichomonas vaginalis on > or =2 occasions between March 2003 and August 2005 found that T. vaginalis may be endemic in this community of African American women.

Trichomonas vaginalis: a review of epidemiologic, clinical and treatment issues

The origins of repeat positives need further explanation and better treatment options are needed, as high rates of retest positive are found among TV infected persons after single dose MTZ treatment.



Sexually Transmitted Infections in Women Infected With the Human Immunodeficiency Virus

A substantial proportion of women developed new STIs during the course of the clinical trial, and prevention efforts should be emphasized among high risk HIV‐infected patients.

Trichomonas vaginalis as a cause of urethritis in Malawian men.

In men with symptomatic urethritis, the median HIV RNA concentration in seminal plasma from men with T. vaginalis was significantly higher that in seminal Plasma from HIV-positive men without trichomonas, and there was no difference in the rate of HIV seropositivity in men with and without T. vaginais.

Cofactors in male-female sexual transmission of human immunodeficiency virus type 1.

Stepwise logistic regression analysis confirmed independent associations between HIV-1 infection and oral contraceptive use, condom use, genital ulcers, and C. trachomatis, and the presence of other sexually transmitted diseases may in part explain the heterosexual HIV- 1 epidemic in Africa.

Non-ulcerative sexually transmitted diseases as risk factors for HIV-1 transmission in women: results from a cohort study.

Non-ulcerative STD were risk factors for sexual transmission of HIV-1 in women, after controlling for sexual exposure, and offered an important additional strategy for the prevention of HIV/AIDS.

Risk factors for trichomoniasis among women with human immunodeficiency virus (HIV) infection at a public clinic in Los Angeles County, California: implications for HIV prevention.

It is suggested that HIV-infected women who are black, and nonblack women who trade sex for money or drugs or are unmarried, are at increased risk of trichomoniasis and therefore may be more likely to transmit HIV infection.

Epidemiological Synergy: Interrelationships between Human Immunodeficiency Virus Infection and Other Sexually Transmitted Diseases

Preliminary data from 83 reports on the impact of HIV infection on STDs suggest that, at a community level, HIV infection may increase the prevalence of some STDs (e.g., genital ulcerative and nonulcerative STDs), and if the same STDs facilitate transmission of HIV, these infections may greatly amplify one another.

Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators.

The recent declines in morbidity and mortality due to AIDS are attributable to the use of more intensive antiretroviral therapies.

Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection.

A study was conducted to evaluate the impact of protease inhibitors on the rates of selected opportunistic processes and mortality in patients with AIDS and found similar results.

Sexual transmission of HIV.

The epidemiology and biology of the host-related factors that affect the sexual transmission of HIV and the host susceptibility and infectiousness environment biologic agent are discussed.