Incidence, predictive factors, and prognosis of chondrosarcoma in patients with Ollier disease and Maffucci syndrome: an international multicenter study of 161 patients.

@article{Verdegaal2011IncidencePF,
  title={Incidence, predictive factors, and prognosis of chondrosarcoma in patients with Ollier disease and Maffucci syndrome: an international multicenter study of 161 patients.},
  author={Suzan H M Verdegaal and Judith V M G Bov{\'e}e and Twinkal C. Pansuriya and Robert J Grimer and Harzem Ozger and Paul C. Jutte and Mikel San Juli{\'a}n and David Biau and INGRID C.M. VAN DER GEEST and Andreas Leithner and Arne Streitbuerger and Frank Michael Klenke and F. Gouin and Domenico Andrea Campanacci and Perrine Marec-Berard and P. C. W. Hogendoorn and Ronald Brand and Antonie H. M. Taminiau},
  journal={The oncologist},
  year={2011},
  volume={16 12},
  pages={1771-9}
}
BACKGROUND Enchondromatosis is characterized by the presence of multiple benign cartilage lesions in bone. While Ollier disease is typified by multiple enchondromas, in Maffucci syndrome these are associated with hemangiomas. Studies evaluating the predictive value of clinical symptoms for development of secondary chondrosarcoma and prognosis are lacking. This multi-institute study evaluates the clinical characteristics of patients, to get better insight on behavior and prognosis of these… CONTINUE READING
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