Incidence, clinical presentation, and outcome of progressive multifocal leukoencephalopathy in HIV-infected patients during the highly active antiretroviral therapy era: a nationwide cohort study.

@article{Engsig2009IncidenceCP,
  title={Incidence, clinical presentation, and outcome of progressive multifocal leukoencephalopathy in HIV-infected patients during the highly active antiretroviral therapy era: a nationwide cohort study.},
  author={Frederik Neess Engsig and A. E. Hansen and Lars Haukali Omland and Gitte Kronborg and Jan Gerstoft and A. L. Laursen and Court Pedersen and Christian Backer Mogensen and Lars Nielsen and Niels Obel},
  journal={The Journal of infectious diseases},
  year={2009},
  volume={199 1},
  pages={77-83}
}
BACKGROUND Human immunodeficiency virus (HIV) infection predisposes to progressive multifocal leukoencephalopathy (PML). Here, we describe the incidence, presentation, and prognosis of PML in HIV-1-infected patients during the period before highly active antiretroviral therapy (HAART) (1995-1996) and during the early HAART (1997-1999) and late HAART (2000-2006) periods. METHODS Patients from a nationwide population-based cohort of adult HIV-1-infected individuals were included. We calculated… CONTINUE READING