Incidence, characterization and prognostic significance of chromosomal abnormalities in 640 patients with primary myelodysplastic syndromes

  title={Incidence, characterization and prognostic significance of chromosomal abnormalities in 640 patients with primary myelodysplastic syndromes},
  author={Sol{\'e} and Espinet and Sanz and Cervera and Calasanz and Lu{\~n}o and Prieto and Granada and Hern{\'a}ndez and Cigudosa and Diez and Bureo and Marqu{\'e}s and Arranz and R{\'i}os and Mart{\'i}nez Climent and Vallesp{\'i} and Florensa and Woessner},
  journal={British Journal of Haematology},
  • Solé, Espinet, +16 authors Woessner
  • Published 2000
  • Medicine
  • British Journal of Haematology
  • Recently, a consensus International Prognostic Scoring System (IPSS) for predicting outcome and planning therapy in the myelodysplastic syndromes (MDS) has been developed. However, the intermediate‐risk cytogenetic subgroup defined by the IPSS includes a miscellaneous number of different single abnormalities for which real prognosis at present is uncertain. The main aims of this study were to evaluate in an independent series the prognostic value of the IPSS and to identify chromosomal… CONTINUE READING
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