Inchinkoto, an herbal medicine, exerts beneficial effects in the rat liver under stress with hepatic ischemia-reperfusion and subsequent hepatectomy.

@article{Kawai2010InchinkotoAH,
  title={Inchinkoto, an herbal medicine, exerts beneficial effects in the rat liver under stress with hepatic ischemia-reperfusion and subsequent hepatectomy.},
  author={Kiyotaka Kawai and Yukihiro Yokoyama and Toshio Kokuryo and Katsutaka Watanabe and Tomomi Kitagawa and M Nagino},
  journal={Annals of surgery},
  year={2010},
  volume={251 4},
  pages={
          692-700
        }
}
OBJECTIVE To investigate the beneficial effects of inchinkoto (ICKT) in the liver after 70% hepatectomy following ischemia reperfusion. METHODS Wistar rats were divided into 3 groups: simple laparotomy and 70% hepatectomy (Hx), 70% hepatectomy following ischemia reperfusion (IR) with vehicle (IRHxV), 70% hepatectomy following IR with ICKT (1 or 2 g/kg of body weight; IRHxK). Vehicle or ICKT was administered for 3 days preoperatively. The hepatoduodenal ligament was clamped for 15 minutes… CONTINUE READING

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