Inbreeding in recessive diseases

  title={Inbreeding in recessive diseases},
  author={Paul Tchen and E. Schulz-Du Bois and Josu{\'e} Feingold and Nicole Feingold and Josselyne Kaplan},
  journal={Human Genetics},
The consanguinity of parents (born in France) of individuals who have a recessive disease has been studied. The frequency of first cousin marriages is less than 0.2% in the general French population. Among the parents of affected individuals the following frequencies of first cousin matings were observed: cystic fibrosis: 1.4% cystinosis: 7.1% nephronophtisis: 5.6% spinal muscular atrophy: 4.5% albinsism: 5.0% achromatopsia: 12.5% (Albinism and spinal muscular atrophy are heterogeneous… CONTINUE READING
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Frrquence de la fibrose kystique du pancrras en France

  • A. E. H. Emery, A. M. Davie, +7 authors M. L. Briard
  • 1974

Le choix du conjoint

  • A. Girard
  • Paris: Presse Universitaire de France
  • 1974
1 Excerpt

Nefronoptisis juvenil familiar , nefropatia tubulointersticial cronica idiopatica , o enfermedad quistica medular

  • G. Gordillo, R. G. Alvarez, L. Bessudo
  • Boletin Medico del Hospital Infantil de Mexico
  • 1967

A genetic study of fibrocystic disease of the pancreas

  • D. M. Danks, J. Allan, C. M. Anderson
  • Genetics
  • 1966

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