Inborn errors of mucocutaneous immunity to Candida albicans in humans: a role for IL-17 cytokines?

@article{Puel2010InbornEO,
  title={Inborn errors of mucocutaneous immunity to Candida albicans in humans: a role for IL-17 cytokines?},
  author={Anne Puel and Capucine Picard and Sophie Cypowyj and Desa Lili{\'c} and Laurent Abel and J. Hugo P{\'e}rez Casanova},
  journal={Current opinion in immunology},
  year={2010},
  volume={22 4},
  pages={467-74}
}
The various clinical manifestations of chronic mucocutaneous candidiasis (CMC) often result from acquired T-cell immunodeficiencies. More rarely, CMC results from inborn errors of immunity, the recent dissection of which has shed light on the molecular mechanisms of mucocutaneous immunity to Candida albicans. CMC may accompany various other infectious diseases in patients with almost any broad and profound T-cell primary immunodeficiency. By contrast, CMC is one of the few key infections in… CONTINUE READING