Inborn errors of metabolism in the light of metabolic control analysis.

@article{Mazat1998InbornEO,
  title={Inborn errors of metabolism in the light of metabolic control analysis.},
  author={J. P. Mazat and T. Letellier and Monique Malgat and Rodrigue Rossignol and Bernard Korzeniewski and France Demaugre and J. P. Leroux},
  journal={Biochemical Society transactions},
  year={1998},
  volume={26 2},
  pages={
          141-5
        }
}
Inborn errors of metabolism in the light of metabolic control analysis J.-P. Mazat', T. Letellier, M. Malgat, R. Rossignol, B. Korzeniewski*, F. Dernaugret and J.-P. Lerouxt Universite Victor SCgalen Bordeaux 2 and CJF-INSERM 9705, I46 rue Leo Saignat, F-33076 Bordeaux Cedex, France, *Institute of Molecular Biology, Jagiellonian University, al. Mickiewicza 3, 3 I I20 Krakow, Poland, and tlNSERM U 75, FacultC de MCdecine Necker-Enfants Malades, 156, rue de Vaugirard-75730, Paris Cedex 15, France… 
View on PubMed
biochemsoctrans.org
5 Citations
Background Citations
1

5 Citations

Citation Type

Citation Type

SNAPSHOTS OF SYSTEMS - METABOLIC CONTROL ANALYSIS AND BIOTECHNOLOGY
TLDR
A critical survey of some of the major limitations of the principles and applications of metabolic control analysis, with special reference to the enhancement of fluxes of biotechnological interest is provided.
Use and limitations of modular metabolic control analysis in medicine and biotechnology.
TLDR
Metabolic Control Analysis has turned out to be helpful in the assessment of the severity of enzyme deficiencies and the search for target enzymes or enzyme groups where pharmaceuticals can suppress the metabolism of pathogenic microorganisms most.
The respiratory chain complex thresholds in mitochondria of a Drosophila subobscura mutant strain.
Dynamics of reactive oxygen intermediate production in human glioma: n‐6 essential fatty acid effects
TLDR
Local essential fatty acid (EFA) deficiencies in tumour cells may limit tumour ROI generation, and this deficiency may be rectified by the addition of exogenous EFA.
Snapshots of Systems
TLDR
It is timely to take stock of progress, to recognize that the take-up of these methods among biotechnologists has been less than widespread, and to give a personal and critical review of successes, failures, problems and prospects for the use of metabolic control analysis in biotechnology.

References

SHOWING 1-2 OF 2 REFERENCES
Understanding the Control of Metabolism
TLDR
Methods for studying metabolism and its regulation traditional approaches to metabolic regulation enzyme activity and the molecular basis for its regulation metabolic control analysis control structures in metabolism are presented.
What is Controlling Life ?
  • Modern Trends in BioThermokinetics
  • 1994