Inappropriate Angiogenic Response as a Novel Mechanism of Duodenal Ulceration and Impaired Healing

@article{Deng2011InappropriateAR,
  title={Inappropriate Angiogenic Response as a Novel Mechanism of Duodenal Ulceration and Impaired Healing},
  author={Xiaoming Deng and Ximing Xiong and T. A. Khomenko and Zsuzsanna Jakabn{\'e} S{\'a}ndor and Kl{\'a}ra Ősapay and Ganna Tolstanova and Joseph Shiloach and Longchuan Chen and Judah M Folkman and S{\'a}ndor Szab{\'o}},
  journal={Digestive Diseases and Sciences},
  year={2011},
  volume={56},
  pages={2792-2801}
}
Despite recent advances and better understanding of the etiology and the pathogenesis of gastrointestinal ulcer diseases, e.g., duodenal ulcer, the molecular events leading to ulcer development, delayed healing, and recurrence remain poorly elucidated. After we found that duodenal ulcers did not heal despite increased levels of vascular endothelial growth factor (VEGF), we tested the hypothesis that an imbalance in angiogenic VEGF and anti-angiogenic endostatin and angiostatin might be… CONTINUE READING
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Angiogenesis and growth factors in ulcer healing

S Szabo, Y Shing, MJ Folkman
2001
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