Inapparent infections and cholera dynamics
@article{King2008InapparentIA, title={Inapparent infections and cholera dynamics}, author={Aaron A. King and Edward L. Ionides and Mercedes Pascual and Menno Bouma}, journal={Nature}, year={2008}, volume={454}, pages={877-880} }
In many infectious diseases, an unknown fraction of infections produce symptoms mild enough to go unrecorded, a fact that can seriously compromise the interpretation of epidemiological records. This is true for cholera, a pandemic bacterial disease, where estimates of the ratio of asymptomatic to symptomatic infections have ranged from 3 to 100 (refs 1–5). In the absence of direct evidence, understanding of fundamental aspects of cholera transmission, immunology and control has been based on…
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