Inadequate aldosterone response to hyperkalemia during angiotensin converting enzyme inhibition in chronic renal failure.

@article{Zanella1985InadequateAR,
  title={Inadequate aldosterone response to hyperkalemia during angiotensin converting enzyme inhibition in chronic renal failure.},
  author={Maria Teresa Zanella and Elisabetta Mattei and S{\'e}rgio Ant{\^o}nio Draibe and Cl{\'a}udio Elias Kater and Horacio Ajzen},
  journal={Clinical pharmacology and therapeutics},
  year={1985},
  volume={38 6},
  pages={613-7}
}
To assess the mechanism involved in hyperkalemia during angiotensin converting enzyme inhibition with captopril in chronic renal failure, captopril, 150 mg/day, was administered to 16 patients with hypertension with plasma creatinine levels between 1.6 and 12.4 mg/dl. After 4 weeks of therapy, plasma potassium levels increased from 3.9 +/- 0.1 to 5.5 +/- 0… CONTINUE READING