Inactive membrane protein kinase Cs: a possible target for receptor signalling.

@article{Chakravarthy1994InactiveMP,
  title={Inactive membrane protein kinase Cs: a possible target for receptor signalling.},
  author={Balu R. Chakravarthy and James F. Whitfield and Jon P. Durkin},
  journal={The Biochemical journal},
  year={1994},
  volume={304 ( Pt 3)},
  pages={
          809-16
        }
}
The activation of the multifunctional cell signalling enzymes, the protein kinase Cs (PKCs), is generally thought to result from the translocation of inactive cytosolic enzymes to activation sites in cell membranes. However, recent studies suggest that PKCs may also be stimulated in cells by processes independent of translocation. One possible mechanism is the modulation of the activity of PKCs already resident in membranes. A PKC assay that measures enzyme activity directly in isolated native… CONTINUE READING
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