Inactivation status of PCDH11X: sexual dimorphisms in gene expression levels in brain

@article{Lopes2006InactivationSO,
  title={Inactivation status of PCDH11X: sexual dimorphisms in gene expression levels in brain},
  author={A. Lopes and N. Ross and J. Close and A. Dagnall and A. Amorim and T. Crow},
  journal={Human Genetics},
  year={2006},
  volume={119},
  pages={267-275}
}
Genes escaping X-inactivation are predicted to contribute to differences in gene dosage between the sexes and are the prime candidates for being involved in the phenotype observed in individuals with X chromosome aneuploidies. Of particular interest is ProtocadherinX (PCDH11X or PCDHX), a recently described gene expressed in brain. In humans, PCDH11X has a homologue on the Y chromosome and is predicted to escape from X-inactivation. Employing bisulphite sequencing analysis we found absence of… Expand
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