Inactivation of the somatosensory cortex prevents paroxysmal oscillations in cortical and related thalamic neurons in a genetic model of absence epilepsy.

@article{Polack2009InactivationOT,
  title={Inactivation of the somatosensory cortex prevents paroxysmal oscillations in cortical and related thalamic neurons in a genetic model of absence epilepsy.},
  author={Pierre-Olivier Polack and S{\'e}verine Mahon and Mario Chavez and St{\'e}phane Charpier},
  journal={Cerebral cortex},
  year={2009},
  volume={19 9},
  pages={2078-91}
}
Absence seizures consist of bilateral spike-and-wave discharges (SWDs) occurring over widespread cortical and thalamic regions. In genetic models of absence epilepsy, recent in vivo investigations indicate that SWDs emerge first in the facial somatosensory cortex and then propagate via the corticothalamocortical loop. The specific involvement of this cortical region in ictogenic processes remained to be established and the participation of its related thalamocortical system in seizure… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 37 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 67 references

Thalamus: organisation and function

M Steriade, EG Jones, DA. McCormick
Oxford: Elsevier Science. • 1997
View 6 Excerpts
Highly Influenced

[The brain in stereotaxic coordinates (a textbook for colleges)].

Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova • 1993
View 3 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…