Inactivation of the Sodium Channel

  title={Inactivation of the Sodium Channel},
  • Published 2003
A B S X R A C T Gating current (I~) has been studied in relation to inactivation of the Na channels. No component of lg has the time course of inactivation; apparent ly little or no charge movement is associated with this step. Inactivation nonetheless affects Ig by immobilizing about two-thirds of gating charge. Immobilization can be followed by measuring… CONTINUE READING