Inactivation of human serum bactericidal activity by a trypsinlike protease isolated from Porphyromonas gingivalis.

  • D. Grenier
  • Published 1992 in Infection and immunity


A protease was isolated from an outer membrane vesicle preparation of Porphyromonas gingivalis ATCC 33277 and assessed for its ability to inactivate the bactericidal activity of normal human serum. The enzyme, which was activated by reducing agents, was found to be a trypsinlike protease with a molecular mass of approximately 80 kDa. Prior to being tested… (More)


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