Inactivation of TRPM7 kinase activity does not impair its channel function in mice

@inproceedings{Kaitsuka2014InactivationOT,
  title={Inactivation of TRPM7 kinase activity does not impair its channel function in mice},
  author={Taku Kaitsuka and Chiaki Katagiri and Pavani Beesetty and Kenji Nakamura and Siham Hourani and Kazuhito Tomizawa and Julius A. Kozak and Masayuki Matsushita},
  booktitle={Scientific reports},
  year={2014}
}
Transient receptor potential (TRP) family channels are involved in sensory pathways and respond to various environmental stimuli. Among the members of this family, TRPM7 is a unique fusion of an ion channel and a C-terminus kinase domain that is highly expressed in immune cells. TRPM7 serves as a key molecule governing cellular Mg(2+) homeostasis in mammals… CONTINUE READING