Inactivation of C3H 10T1/2 cells by monoenergetic high LET alpha-particles.

  title={Inactivation of C3H 10T1/2 cells by monoenergetic high LET alpha-particles.},
  author={Maria Napolitano and Marco Durante and Giovanna Grossi and M. Pugliese and Giancarlo Gialanella},
  journal={International journal of radiation biology},
  volume={61 6},
Inactivation of mouse C3H 10T1/2 cells in plateau-phase (7.8 x 10(4) cells/cm2) was studied by using alpha-particles from the irradiation facility installed for radiobiological experiments at the 3 MV Tandem accelerator, University of Naples. Silicon detectors and CR39 plastic track detectors were employed for dosimetric purposes. The cells were exposed to high LET monoenergetic alpha-particles (energy of 1.8 MeV at the centre of the cell nucleus, track-averaged LET of 177 keV/micron and dose… CONTINUE READING