Inactivation and morphological changes of avian influenza virus by copper ions

@article{Horie2008InactivationAM,
  title={Inactivation and morphological changes of avian influenza virus by copper ions},
  author={Masayuki Horie and Haruko Ogawa and Yu Yoshida and Kentaro Yamada and Aritsugu Hara and Kouhei Ozawa and Shigeo Matsuda and Chiaki Mizota and Minobu Tani and Yumiko Yamamoto and Minoru Yamada and Kikuyasu Nakamura and Tomofumi Santa},
  journal={Archives of Virology},
  year={2008},
  volume={153},
  pages={1467-1472}
}
The infectivity of the H9N2 virus to MDCK cells was time-dependently inhibited by Cu2+ at concentrations of 2.5–250 μM. In 25 μM Cu2+ solution, the virus titer decreased by approximately 3 and 4 log within 3 and 6 h, respectively. Compared to Cu2+, Zn2+ was much less effective in virus inactivation. The H9N2 virus hemagglutinin activity was not affected by 2.5–250 μM Cu2+. The H9N2 virus neuraminidase (NA) activity was drastically reduced by 25 mM Cu2+, marginally reduced by 250 μM Cu2+, and… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 23 REFERENCES

Copper as a biocidal tool.

  • Current medicinal chemistry
  • 2005
VIEW 1 EXCERPT

Studies on the feeding of cupric sulfate pentahydrate, cupric citrate, and copper oxychloride to broiler chickens

HP Ewing, GM Pesti, RI Bakalli, JFM Menten
  • Poult Sci
  • 1998

Role of plasma membrane ganglioside sialidase of human neuroblastoma cells in growth control and differentiation

J Kopitz, C von Reitzenstein, C Mühl, M Cantz
  • Biochem Biophys Res Commun
  • 1994
VIEW 1 EXCERPT

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